MHCclassII

與MHCI不同,MHCII旨在將病原體呈現在細胞外而不是細胞內。此外,第一步是通過吞噬作用獲得病原體。然後病原體在溶酶體中被降解以回收感興趣的成分並將它們加載到MHC ...,BecauseclassIIMHCisloadedwithextracellularproteins,itismainlyconcernedwithpresentationofextracellularpathogens(forexample,bacteriathat ...,2013年10月31日—從生物化學的角度來看,由於每種MHC分子只會依靠被結合的胜肽鏈上的2個胺基酸就能與之穩...

mhc 二級Mhc Class Ii

與MHC I 不同,MHC II 旨在將病原體呈現在細胞外而不是細胞內。此外,第一步是通過吞噬作用獲得病原體。然後病原體在溶酶體中被降解以回收感興趣的成分並將它們加載到MHC ...

MHC class II

Because class II MHC is loaded with extracellular proteins, it is mainly concerned with presentation of extracellular pathogens (for example, bacteria that ...

主要組織相容性複合物

2013年10月31日 — 從生物化學的角度來看,由於每種MHC 分子只會依靠被結合的胜肽鏈上的2 個胺基酸就能與之穩定結合,因此一種MHC 分子就能結合數以百萬計的胜肽。 至於第二 ...

Endogenous MHC Class II Processing of a Viral Nuclear ...

2015年8月24日 — Endogenous MHC Class II Processing of a Viral Nuclear Antigen After Autophagy. Science 307: 593-596. Speaker : 鄭達恩 Time: 14:00-15:00 ...

MHC class II antigen presentation and immunological ...

由 X Chen 著作 · 2008 · 被引用 52 次 — Antigen presentation by Major Histocompatibility Complex (MHC) class II molecules plays an important role in controlling immunity and autoimmunity.

Function and regulation of MHC class II molecules in T

由 TM Holling 著作 · 2004 · 被引用 415 次 — The main function of major histocompatibility complex (MHC) class II molecules is to present processed antigens, which are derived primarily from exogenous ...

MHC class II molecules on the move for successful antigen ...

由 N Rocha 著作 · 2007 · 被引用 217 次 — Major histocompatibility complex class II molecules (MHC II) are expressed by immune cells like B cells, dendritic cells (DCs), and monocytes/macrophages and ...

The ins and outs of MHC class II

由 PA Roche 著作 · 2015 · 被引用 1056 次 — MHC class II binds antigenic peptides that are generated by proteolysis of self and non-self proteins in endosomes and lysosomes, and 'presents' ...

MHC Class II

The hallmark of MHC class II deficiency is the absence of HLA-DR, -DQ and -DP molecules on B cells, monocytes and dendritic cells (which constitutively express ...